In a large skillet, heat over medium-high heat. Once hot, add the ground beef and season it with garlic powder, onion powder, paprika, salt, and black pepper. Cook for about 8-10 minutes, breaking it up as you go until it's browned and fully cooked.
While the beef cooks, combine the Greek yogurt, mustard, and ketchup in a small bowl. Mix well until smooth to create a tasty sauce.
Once the beef is finished cooking, remove it from the heat and let it rest for a couple of minutes. Meanwhile, prepare the serving bowls by layering a base of chopped romaine.
Top the lettuce with the cooked beef mixture, followed by the halved cherry tomatoes, dill pickles, sliced red onion, and a generous sprinkle of sharp cheddar cheese.
Drizzle the bowls with the prepared sauce and serve immediately for a delicious, protein-packed meal.