In a medium bowl, mix ground beef with the salt, black pepper, and garlic powder. Be careful not to overmix; just stir until it's combined for tender patties.
Shape the meat into two even-sized patties, making them slightly larger than your bread slices. This helps with shrinkage during cooking.
Heat a skillet over medium-high heat and place the patties in. Cook them until browned on both sides and until they're cooked to your liking.
Add one slice of cheese to each patty during the last minute of cooking. Cover the skillet with a lid to help the cheese melt beautifully.
Spread softened butter or mayo on one side of each slice of bread. This adds a rich flavor and helps get that perfect golden color when grilled.
For each sandwich, layer two slices of cheese between two slices of the buttered bread. This creates a gooey center that everyone will love.
In a clean skillet, grill the sandwiches over medium heat. Flip them carefully to achieve golden brown on both sides, allowing the cheese inside to get all melty.
Place one of the grilled burger patties inside each grilled cheese sandwich. Serve them warm for an incredibly comforting meal.